A deluxe bind-up edition of Naoki Urasawa's award-winning epic of doomsday cults, giant robots and a group of friends trying to save the world from destruction! Humanity, having faced extinction at the end of the 20th century, would not have entered the new millennium if it weren't for them. In 1969, during their youth, they created a symbol. In 1997, as the coming disaster slowly starts to unfold, that symbol returns. This is the story of a group of boys who try to save the world. Kanna, burdened by the fact that her mother Kiriko developed the bacteriological weapons used by the Friends on Bloody New Year's Eve, ruminates over the ominous messages she left behind. When the weapons come back to haunt humanity, Kanna isn't the only one searching for traces of Kiriko. Otcho gets closer to finding out the missing doctor's current whereabouts after a search leads him to her former colleague, Dr. Yamane.